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Dynamics of Neuromuscular Transmission Reproduced by Calcium-Dependent and Reversible Serial Transitions in the Vesicle Fusion Complex
Neuromuscular transmission, from spontaneous release to facilitation and depression, was accurately reproduced by a mechanistic kinetic model of sequential maturation transitions in the molecular fusion complex. The model incorporates three predictions. First, calcium-dependent forward transitions t...
Autores principales: | Martínez-Valencia, Alejandro, Ramírez-Santiago, Guillermo, De-Miguel, Francisco F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885725/ https://www.ncbi.nlm.nih.gov/pubmed/35242023 http://dx.doi.org/10.3389/fnsyn.2021.785361 |
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