Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss

Bone loss due to an increased osteoclast activity is common in osteoporosis and rheumatoid arthritis. For the first time, we observed an inhibition of osteoclast formation and bone resorption by outer-membrane vesicles (OMVs) from a Gram-negative, pathogenic bacterium, Proteus mirabilis (P.M). Gene...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Mo, Lixia, Ou, Jiaxin, Fang, Qinghua, Wu, Huimei, Wu, Yuzhe, Nandakumar, Kutty Selva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885728/
https://www.ncbi.nlm.nih.gov/pubmed/35242136
http://dx.doi.org/10.3389/fimmu.2022.833040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885728/
https://www.ncbi.nlm.nih.gov/pubmed/35242136
http://dx.doi.org/10.3389/fimmu.2022.833040

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