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In silico and in vitro protocols for quantifying gene expression noise modulated by microRNAs
Characterizing the noise modulation pattern of microRNA is valuable for both microRNA function analysis and synthetic biology applications. Here we propose a coarse-grained model to simulate how the properties of microRNAs, competing RNAs, and microRNA response elements affect gene expression noise....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885741/ https://www.ncbi.nlm.nih.gov/pubmed/35243382 http://dx.doi.org/10.1016/j.xpro.2022.101205 |