In silico and in vitro protocols for quantifying gene expression noise modulated by microRNAs

Characterizing the noise modulation pattern of microRNA is valuable for both microRNA function analysis and synthetic biology applications. Here we propose a coarse-grained model to simulate how the properties of microRNAs, competing RNAs, and microRNA response elements affect gene expression noise....

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Detalles Bibliográficos
Autores principales: Wei, Lei, Li, Shuailin, Wang, Xiaowo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885741/
https://www.ncbi.nlm.nih.gov/pubmed/35243382
http://dx.doi.org/10.1016/j.xpro.2022.101205

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