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An optimized protocol for PD-L1 pathological assessment with patient sample deglycosylation to improve correlation with therapeutic response

Immunotherapy via PD-1/PD-L1 blockade is a promising strategy to eradicate cancer cells. However, the PD-L1 pathological level is inconsistent with the therapeutic response and is not a reliable biomarker to stratify patients for anti-PD-1/PD-L1 therapy. Here, we describe patient sample deglycosylat...

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Detalles Bibliográficos
Autores principales: Wang, Ying-Nai, Lee, Heng-Huan, Wei, Yongkun, Chu, Yu-Yi, Xia, Weiya, Wang, Michael, Yu, Dihua, Hung, Mien-Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885744/
https://www.ncbi.nlm.nih.gov/pubmed/35243381
http://dx.doi.org/10.1016/j.xpro.2022.101198