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NLRP3 Inhibitor Tranilast Attenuates Gestational Diabetes Mellitus in a Genetic Mouse Model
BACKGROUND AND OBJECTIVE: This study was designed to explore the protective effects of a clinically available NLR family Pyrin domain-containing receptor 3 (NLRP3) inhibitor, tranilast, in gestational diabetes mellitus (GDM) mice. METHODS: We used pregnant C57BL/KsJdb/+ (db/+) female mice as GDM mic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885922/ https://www.ncbi.nlm.nih.gov/pubmed/35124792 http://dx.doi.org/10.1007/s40268-022-00382-7 |