GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease

Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood, limiting the development of therapies directed at disease-relevant molecu...

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Detalles Bibliográficos
Autores principales: McIntyre, Lauren M., Huertas, Francisco, Morse, Alison M., Kaletsky, Rachel, Murphy, Coleen T., Kalia, Vrinda, Miller, Gary W., Moskalenko, Olexander, Conesa, Ana, Mor, Danielle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885929/
https://www.ncbi.nlm.nih.gov/pubmed/35228596
http://dx.doi.org/10.1038/s41598-022-07238-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885929/
https://www.ncbi.nlm.nih.gov/pubmed/35228596
http://dx.doi.org/10.1038/s41598-022-07238-9

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