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GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease
Parkinson’s disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood, limiting the development of therapies directed at disease-relevant molecu...
Autores principales: | McIntyre, Lauren M., Huertas, Francisco, Morse, Alison M., Kaletsky, Rachel, Murphy, Coleen T., Kalia, Vrinda, Miller, Gary W., Moskalenko, Olexander, Conesa, Ana, Mor, Danielle E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885929/ https://www.ncbi.nlm.nih.gov/pubmed/35228596 http://dx.doi.org/10.1038/s41598-022-07238-9 |
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