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Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway

Nocturnal polyuria is the most frequent cause of nocturia, a common disease associated with a compromised quality of life and increased mortality. Its pathogenesis is complex, and the detailed underlying mechanism remains unknown. Herein, we report that concomitant intake of a high-salt diet and red...

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Detalles Bibliográficos
Autores principales: Sekii, Y., Kiuchi, H., Takezawa, K., Imanaka, T., Kuribayashi, S., Okada, K., Inagaki, Y., Ueda, N., Fukuhara, S., Imamura, R., Negoro, H., Nonomura, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885931/
https://www.ncbi.nlm.nih.gov/pubmed/35228649
http://dx.doi.org/10.1038/s42003-022-03104-6