Neutralization of HMGB1 improves fracture healing and γδ T lymphocyte counts at the fracture site in a polytrauma rat model

PURPOSE: Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels in blood, they dysregulate immune responses as...

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Detalles Bibliográficos
Autores principales: Muire, Preeti J., Avila, Joshua J., Lofgren, Alicia L., Wenke, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885932/
https://www.ncbi.nlm.nih.gov/pubmed/35229226
http://dx.doi.org/10.1186/s40634-022-00453-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885932/
https://www.ncbi.nlm.nih.gov/pubmed/35229226
http://dx.doi.org/10.1186/s40634-022-00453-3

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