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Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress

BACKGROUND: Ischemic stroke (IS) is a common disease endangering human life and health. Cerebral ischemia triggers a series of complex harmful events, including excitotoxicity, inflammation and cell death, as well as increased nitric oxide production through the activation of nitric oxide synthase (...

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Detalles Bibliográficos
Autores principales: Fan, Xuehui, Chen, Hongping, Xu, Chen, Wang, Yingju, Yin, Pengqi, Li, Meng, Tang, Zhanbin, Jiang, Fangchao, Wei, Wan, Song, Jihe, Li, Guozhong, Zhong, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886115/
https://www.ncbi.nlm.nih.gov/pubmed/35242008
http://dx.doi.org/10.3389/fnins.2022.838621