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Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials. This may be because the presence of enlarged collaterals is not su...

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Detalles Bibliográficos
Autores principales: Silva, Alexander, Hatch, Christopher J., Chu, Megan T., Cardinal, Trevor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886147/
https://www.ncbi.nlm.nih.gov/pubmed/35242824
http://dx.doi.org/10.3389/fcvm.2022.805810