Cargando…

Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells

Thymopentin (TP5) is an immunomodulatory pentapeptide that has been widely used in malignancy patients with immunodeficiency due to radiotherapy and chemotherapy. Here, we propose that TP5 directly inhibits the stemness of colon cancer cells HCT116 and therefore enhances the cytotoxicity of oxalipla...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Peng-Cheng, Liu, Di, Han, Zeng-Xiang, Liang, Fang, Hao, Cui-Yun, Lei, Yun-Tao, Guo, Chang-Run, Wang, Wen-Hui, Li, Xing-Hua, Yang, Xiao-Na, Li, Chang-Zhu, Yu, Ye, Fan, Ying-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886222/
https://www.ncbi.nlm.nih.gov/pubmed/35242031
http://dx.doi.org/10.3389/fphar.2022.779715