Suppression of FoxO1 mRNA by β(2)‐adrenoceptor–cAMP signaling through miR‐374b‐5p and miR‐7a‐1‐3p in C2C12 myotubes

β(2)‐Adrenoceptor (β(2)‐AR) signaling decreases the transcriptional activity of forkhead box O (FoxO), but the underlying mechanisms remain incompletely understood. Here, we investigated how β(2)‐AR signaling regulates the protein abundance of FoxO and its transcriptional activity in skeletal muscle...

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Detalles Bibliográficos
Autores principales: Shimamoto, Saki, Nakashima, Kazuki, Nishikoba, Nao, Kohrogi, Rukana, Ohtsuka, Akira, Fujimura, Shinobu, Ijiri, Daichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886325/
https://www.ncbi.nlm.nih.gov/pubmed/35038382
http://dx.doi.org/10.1002/2211-5463.13368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886325/
https://www.ncbi.nlm.nih.gov/pubmed/35038382
http://dx.doi.org/10.1002/2211-5463.13368

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