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Suppression of FoxO1 mRNA by β(2)‐adrenoceptor–cAMP signaling through miR‐374b‐5p and miR‐7a‐1‐3p in C2C12 myotubes
β(2)‐Adrenoceptor (β(2)‐AR) signaling decreases the transcriptional activity of forkhead box O (FoxO), but the underlying mechanisms remain incompletely understood. Here, we investigated how β(2)‐AR signaling regulates the protein abundance of FoxO and its transcriptional activity in skeletal muscle...
Autores principales: | Shimamoto, Saki, Nakashima, Kazuki, Nishikoba, Nao, Kohrogi, Rukana, Ohtsuka, Akira, Fujimura, Shinobu, Ijiri, Daichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886325/ https://www.ncbi.nlm.nih.gov/pubmed/35038382 http://dx.doi.org/10.1002/2211-5463.13368 |
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