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The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR‐Cas9 screen

Certain cancers, such as ovarian clear cell carcinoma (OCCC), display high levels of genetic variation between patients, making it difficult to develop effective therapies. In order to identify novel genes critical to OCCC growth, we carried out a comprehensive CRISPR‐Cas9 knockout screen against ce...

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Detalles Bibliográficos
Autores principales: Cona, Brandon, Hayashi, Tomoatsu, Yamada, Ai, Shimizu, Naomi, Yokota, Naoko, Nakato, Ryuichiro, Shirahige, Katsuhiko, Akiyama, Tetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886329/
https://www.ncbi.nlm.nih.gov/pubmed/34965029
http://dx.doi.org/10.1002/2211-5463.13358