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Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II

Nucleosomes are disrupted transiently during eukaryotic transcription, yet the displaced histones must be retained and redeposited onto DNA, to preserve nucleosome density and associated histone modifications. Here, we show that the essential Spt5 processivity factor of RNA polymerase II (Pol II) pl...

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Detalles Bibliográficos
Autores principales: Evrin, Cecile, Serra‐Cardona, Albert, Duan, Shoufu, Mukherjee, Progya P, Zhang, Zhiguo, Labib, Karim P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886531/
https://www.ncbi.nlm.nih.gov/pubmed/35102600
http://dx.doi.org/10.15252/embj.2021109783