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SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation
The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim). Since cellular replication protein A (RPA) prevents primase from starting RNA synthesis on...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886539/ https://www.ncbi.nlm.nih.gov/pubmed/35073603 http://dx.doi.org/10.1002/2211-5463.13373 |