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Critical review of nucleic acid nanotechnology to identify gaps and inform a strategy for accelerated clinical translation

With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now poised for clinical translation supported by several examples of FDA-approved nucleic acid nanoformulations including two recent mRNA-based COVID-19 vaccines. Within this rapidly growing field, a new subclass...

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Detalles Bibliográficos
Autores principales: Afonin, Kirill A., Dobrovolskaia, Marina A., Ke, Weina, Grodzinski, Piotr, Bathe, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886801/
https://www.ncbi.nlm.nih.gov/pubmed/34915069
http://dx.doi.org/10.1016/j.addr.2021.114081