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Critical review of nucleic acid nanotechnology to identify gaps and inform a strategy for accelerated clinical translation
With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now poised for clinical translation supported by several examples of FDA-approved nucleic acid nanoformulations including two recent mRNA-based COVID-19 vaccines. Within this rapidly growing field, a new subclass...
Autores principales: | Afonin, Kirill A., Dobrovolskaia, Marina A., Ke, Weina, Grodzinski, Piotr, Bathe, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886801/ https://www.ncbi.nlm.nih.gov/pubmed/34915069 http://dx.doi.org/10.1016/j.addr.2021.114081 |
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