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The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells (†)

Here we report on the related TBC/RabGAPs EPI64A and EPI64B and show that they function to organize the apical aspect of epithelial cells. EPI64A binds the scaffolding protein EBP50/NHERF1, which itself binds active ezrin in epithelial cell microvilli. Epithelial cells additionally express EPI64B th...

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Detalles Bibliográficos
Autores principales: Miller, Matthew R., McDermitt, David J., Sauvanet, Cecile, Lombardo, Andrew T., Zaman,, Riasat, Bretscher, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886810/
https://www.ncbi.nlm.nih.gov/pubmed/34757852
http://dx.doi.org/10.1091/mbc.E21-05-0268