Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism

Class III myosins are actin-based motors proposed to transport cargo to the distal tips of stereocilia in the inner ear hair cells and/or to participate in stereocilia length regulation, which is especially important during development. Mutations in the MYO3A gene are associated with delayed onset d...

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Detalles Bibliográficos
Autores principales: Gunther, Laura K., Cirilo, Joseph A., Desetty, Rohini, Yengo, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886822/
https://www.ncbi.nlm.nih.gov/pubmed/34788109
http://dx.doi.org/10.1091/mbc.E21-05-0232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886822/
https://www.ncbi.nlm.nih.gov/pubmed/34788109
http://dx.doi.org/10.1091/mbc.E21-05-0232

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