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Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism
Class III myosins are actin-based motors proposed to transport cargo to the distal tips of stereocilia in the inner ear hair cells and/or to participate in stereocilia length regulation, which is especially important during development. Mutations in the MYO3A gene are associated with delayed onset d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886822/ https://www.ncbi.nlm.nih.gov/pubmed/34788109 http://dx.doi.org/10.1091/mbc.E21-05-0232 |