Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF

BACKGROUND: Multiple morphological abnormalities of the sperm flagella (MMAF) is a subtype of severe asthenoteratozoospermia with poorly understood genetic etiology. SPAG6 is a core axonemal component that plays a critical role in the formation of cilia and sperm flagella. Previous studies have repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Chuan, Tang, Dongdong, Shao, Zhongmei, Geng, Hao, Gao, Yang, Li, Kuokuo, Tan, Qing, Wang, Guanxiong, Wang, Chao, Wu, Huan, Li, Guanjian, Lv, Mingrong, He, Xiaojin, Cao, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886842/
https://www.ncbi.nlm.nih.gov/pubmed/35232447
http://dx.doi.org/10.1186/s12958-022-00916-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886842/
https://www.ncbi.nlm.nih.gov/pubmed/35232447
http://dx.doi.org/10.1186/s12958-022-00916-3

Ejemplares similares