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Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF

BACKGROUND: Multiple morphological abnormalities of the sperm flagella (MMAF) is a subtype of severe asthenoteratozoospermia with poorly understood genetic etiology. SPAG6 is a core axonemal component that plays a critical role in the formation of cilia and sperm flagella. Previous studies have repo...

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Detalles Bibliográficos
Autores principales:	Xu, Chuan, Tang, Dongdong, Shao, Zhongmei, Geng, Hao, Gao, Yang, Li, Kuokuo, Tan, Qing, Wang, Guanxiong, Wang, Chao, Wu, Huan, Li, Guanjian, Lv, Mingrong, He, Xiaojin, Cao, Yunxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886842/ https://www.ncbi.nlm.nih.gov/pubmed/35232447 http://dx.doi.org/10.1186/s12958-022-00916-3

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