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Accurate expression quantification from nanopore direct RNA sequencing with NanoCount

Accurately quantifying gene and isoform expression changes is essential to understanding cell functions, differentiation and disease. Sequencing full-length native RNAs using long-read direct RNA sequencing (DRS) has the potential to overcome many limitations of short and long-read sequencing method...

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Detalles Bibliográficos
Autores principales: Gleeson, Josie, Leger, Adrien, Prawer, Yair D J, Lane, Tracy A, Harrison, Paul J, Haerty, Wilfried, Clark, Michael B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886870/
https://www.ncbi.nlm.nih.gov/pubmed/34850115
http://dx.doi.org/10.1093/nar/gkab1129