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Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency

BACKGROUND: Bone morphogenetic protein 15 (BMP15) is expressed in oocytes and plays a crucial role in the reproduction of mono-ovulating species. In humans, BMP15 gene mutations lead to imperfect protein function and premature ovarian insufficiency. Here we investigated the BMP15 gene variants in a...

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Detalles Bibliográficos
Autores principales: Afkhami, Fatemeh, Shahbazi, Shirin, Farzadi, Laya, Danaei, Shahla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886931/
https://www.ncbi.nlm.nih.gov/pubmed/35232444
http://dx.doi.org/10.1186/s12958-022-00913-6