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Molnupiravir (MK-4482) is efficacious against Omicron and other SARS-CoV-2 variants in the Syrian hamster COVID-19 model

The recent emergence of the SARS-CoV-2 Omicron variant of concern (VOC) containing a heavily mutated spike protein capable of escaping preexisting immunity, identifies a continued need for interventional measures. Molnupiravir (MK-4482), an orally administered nucleoside analog, has demonstrated eff...

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Detalles Bibliográficos
Autores principales: Rosenke, Kyle, Okumura, Atsushi, Lewis, Matthew C., Feldmann, Friederike, Meade-White, Kimberly, Bohler, W. Forrest, Griffin, Amanda, Rosenke, Rebecca, Shaia, Carl, Jarvis, Michael A., Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887072/
https://www.ncbi.nlm.nih.gov/pubmed/35233571
http://dx.doi.org/10.1101/2022.02.22.481491