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Differential escape of neutralizing antibodies by SARS-CoV-2 Omicron and pre-emergent sarbecoviruses

The SARS-CoV-2 B.1.1.529 lineage, Omicron variant, was first detected in November 2021 and carries 32 amino acid mutations in the spike protein (15 in RBD) and exhibits significant escape of neutralizing antibodies targeting the parental SARS-CoV-2 virus. Here, we performed a high-resolution multipl...

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Detalles Bibliográficos
Autores principales: Wang, Lin-Fa, Tan, Chee Wah, Chia, Wan Ni, Zhu, Feng, Young, Barnaby, Chantasrisawad, Napaporn, Hwa, Shi-Hsia, Yeoh, Aileen Ying-Yan, Lim, Beng Lee, Yap, Wee Chee, Pada, Surinder Kaur, Tan, Seow Yen, Jantarabenjakul, Watsamon, Chen, Shiwei, Zhang, Jinyan, Mah, Yun Yan, Chen, Vivian, Chen, Mark, Wacharapluesadee, Supaporn, Putcharoen, Opass, Lye, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887082/
https://www.ncbi.nlm.nih.gov/pubmed/35233568
http://dx.doi.org/10.21203/rs.3.rs-1362541/v1