Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance

Ctf4 is a conserved replisome component with multiple roles in DNA metabolism. To investigate connections between Ctf4-mediated processes involved in drug resistance, we conducted a suppressor screen of ctf4Δ sensitivity to the methylating agent MMS. We uncovered that mutations in Dpb3 and Dpb4 comp...

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Detalles Bibliográficos
Autores principales: Dolce, Valeria, Dusi, Sabrina, Giannattasio, Michele, Joseph, Chinnu Rose, Fumasoni, Marco, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887126/
https://www.ncbi.nlm.nih.gov/pubmed/35115379
http://dx.doi.org/10.1101/gad.349207.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887126/
https://www.ncbi.nlm.nih.gov/pubmed/35115379
http://dx.doi.org/10.1101/gad.349207.121

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