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Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance

Ctf4 is a conserved replisome component with multiple roles in DNA metabolism. To investigate connections between Ctf4-mediated processes involved in drug resistance, we conducted a suppressor screen of ctf4Δ sensitivity to the methylating agent MMS. We uncovered that mutations in Dpb3 and Dpb4 comp...

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Detalles Bibliográficos
Autores principales:	Dolce, Valeria, Dusi, Sabrina, Giannattasio, Michele, Joseph, Chinnu Rose, Fumasoni, Marco, Branzei, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887126/ https://www.ncbi.nlm.nih.gov/pubmed/35115379 http://dx.doi.org/10.1101/gad.349207.121

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