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BMAL1 drives muscle repair through control of hypoxic NAD(+) regeneration in satellite cells

The process of tissue regeneration occurs in a developmentally timed manner, yet the role of circadian timing is not understood. Here, we identify a role for the adult muscle stem cell (MuSC)-autonomous clock in the control of muscle regeneration following acute ischemic injury. We observed greater...

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Detalles Bibliográficos
Autores principales: Zhu, Pei, Hamlish, Noah X., Thakkar, Abhishek Vijay, Steffeck, Adam W.T., Rendleman, Emily J., Khan, Nabiha H., Waldeck, Nathan J., DeVilbiss, Andrew W., Martin-Sandoval, Misty S., Mathews, Thomas P., Chandel, Navdeep S., Peek, Clara B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887128/
https://www.ncbi.nlm.nih.gov/pubmed/35115380
http://dx.doi.org/10.1101/gad.349066.121