Reconstitution of 3′ end processing of mammalian pre-mRNA reveals a central role of RBBP6

The 3′ ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction: endonucleolytic cleavage of an extended precursor followed by the addition of a poly(A) tail. By reconstituting the reaction from overproduced and purified proteins, we provide a minimal list of 14...

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Detalles Bibliográficos
Autores principales: Schmidt, Moritz, Kluge, Florian, Sandmeir, Felix, Kühn, Uwe, Schäfer, Peter, Tüting, Christian, Ihling, Christian, Conti, Elena, Wahle, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887130/
https://www.ncbi.nlm.nih.gov/pubmed/35177537
http://dx.doi.org/10.1101/gad.349217.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887130/
https://www.ncbi.nlm.nih.gov/pubmed/35177537
http://dx.doi.org/10.1101/gad.349217.121

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