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Cell-type heterogeneity: Why we should adjust for it in epigenome and biomarker studies
Most studies aiming to identify epigenetic biomarkers do so from complex tissues that are composed of many different cell-types. By definition, these cell-types vary substantially in terms of their epigenetic profiles. This cell-type specific variation among healthy cells is completely independent o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887190/ https://www.ncbi.nlm.nih.gov/pubmed/35227298 http://dx.doi.org/10.1186/s13148-022-01253-3 |