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RNA modifications stabilize the tertiary structure of tRNA(fMet) by locally increasing conformational dynamics

A plethora of modified nucleotides extends the chemical and conformational space for natural occurring RNAs. tRNAs constitute the class of RNAs with the highest modification rate. The extensive modification modulates their overall stability, the fidelity and efficiency of translation. However, the i...

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Detalles Bibliográficos
Autores principales: Biedenbänder, Thomas, de Jesus, Vanessa, Schmidt-Dengler, Martina, Helm, Mark, Corzilius, Björn, Fürtig, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887418/
https://www.ncbi.nlm.nih.gov/pubmed/35137185
http://dx.doi.org/10.1093/nar/gkac040