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Chaperone mediated autophagy contributes to the newly synthesized histones H3 and H4 quality control

Although there are several pathways to ensure that proteins are folded properly in the cell, little is known about the molecular mechanisms regulating histone folding and proteostasis. In this work, we identified that chaperone-mediated autophagy (CMA) is the main pathway involved in the degradation...

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Detalles Bibliográficos
Autores principales: Hormazabal, Juan, Saavedra, Francisco, Espinoza-Arratia, Claudia, Martinez, Nicolas W, Cruces, Tatiana, Alfaro, Iván E, Loyola, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887419/
https://www.ncbi.nlm.nih.gov/pubmed/35037039
http://dx.doi.org/10.1093/nar/gkab1296