Cargando…
Chaperone mediated autophagy contributes to the newly synthesized histones H3 and H4 quality control
Although there are several pathways to ensure that proteins are folded properly in the cell, little is known about the molecular mechanisms regulating histone folding and proteostasis. In this work, we identified that chaperone-mediated autophagy (CMA) is the main pathway involved in the degradation...
Autores principales: | Hormazabal, Juan, Saavedra, Francisco, Espinoza-Arratia, Claudia, Martinez, Nicolas W, Cruces, Tatiana, Alfaro, Iván E, Loyola, Alejandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887419/ https://www.ncbi.nlm.nih.gov/pubmed/35037039 http://dx.doi.org/10.1093/nar/gkab1296 |
Ejemplares similares
-
PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4
por: Saavedra, Francisco, et al.
Publicado: (2017) -
The activity of the histone chaperone yeast Asf1 in the assembly and disassembly of histone H3/H4–DNA complexes
por: Donham, Douglas C., et al.
Publicado: (2011) -
CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA
por: Liu, Wallace H., et al.
Publicado: (2012) -
The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3–H4 tetramers and Asf1–H3–H4 complexes
por: Hammond, Colin M., et al.
Publicado: (2016) -
Histone chaperone Chz1p regulates H2B ubiquitination and subtelomeric anti-silencing
por: Wan, Yakun, et al.
Publicado: (2010)