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Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci

The first member of the pleuromutilin (PLM) class suitable for systemic antibacterial chemotherapy in humans recently entered clinical use, underscoring the need to better understand mechanisms of PLM resistance in disease-causing bacterial genera. Of the proteins reported to mediate PLM resistance...

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Detalles Bibliográficos
Autores principales: Mohamad, Merianne, Nicholson, David, Saha, Chayan Kumar, Hauryliuk, Vasili, Edwards, Thomas A, Atkinson, Gemma C, Ranson, Neil A, O’Neill, Alex J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887462/
https://www.ncbi.nlm.nih.gov/pubmed/35137182
http://dx.doi.org/10.1093/nar/gkac058