Synthetic robust perfect adaptation achieved by negative feedback coupling with linear weak positive feedback

Unlike their natural counterparts, synthetic genetic circuits are usually fragile in the face of environmental perturbations and genetic mutations. Several theoretical robust genetic circuits have been designed, but their performance under real-world conditions has not yet been carefully evaluated....

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Detalles Bibliográficos
Autores principales: Sun, Zhi, Wei, Weijia, Zhang, Mingyue, Shi, Wenjia, Zong, Yeqing, Chen, Yihua, Yang, Xiaojing, Yu, Bo, Tang, Chao, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887471/
https://www.ncbi.nlm.nih.gov/pubmed/35166832
http://dx.doi.org/10.1093/nar/gkac066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887471/
https://www.ncbi.nlm.nih.gov/pubmed/35166832
http://dx.doi.org/10.1093/nar/gkac066

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