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Gain of C-Ala enables AlaRS to target the L-shaped tRNA(Ala)
Unlike many other aminoacyl-tRNA synthetases, alanyl-tRNA synthetase (AlaRS) retains a conserved prototype structure throughout biology. While Caenorhabditis elegans cytoplasmic AlaRS (CeAlaRS(c)) retains the prototype structure, its mitochondrial counterpart (CeAlaRS(m)) contains only a residual C-...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887476/ https://www.ncbi.nlm.nih.gov/pubmed/35100402 http://dx.doi.org/10.1093/nar/gkac026 |