The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3′X point to conserved regulatory mechanisms within the Flaviviridae family

Subdomain 5BSL3.2 of hepatitis C virus RNA lies at the core of a network of distal RNA–RNA contacts that connect the 5′ and 3′ regions of the viral genome and regulate the translation and replication stages of the viral cycle. Using small-angle X-ray scattering and NMR spectroscopy experiments, we h...

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Detalles Bibliográficos
Autores principales: Castillo-Martínez, Jesús, Fan, Lixin, Szewczyk, Mateusz P, Wang, Yun-Xing, Gallego, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887478/
https://www.ncbi.nlm.nih.gov/pubmed/35137150
http://dx.doi.org/10.1093/nar/gkac061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887478/
https://www.ncbi.nlm.nih.gov/pubmed/35137150
http://dx.doi.org/10.1093/nar/gkac061

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