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Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel

The ribosome is a fundamental biomolecular complex that synthesizes proteins in cells. Nascent proteins emerge from the ribosome through a tunnel, where they may interact with the tunnel walls or small molecules such as antibiotics. These interactions can cause translational arrest with notable phys...

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Detalles Bibliográficos
Autores principales: Kolář, Michal H, Nagy, Gabor, Kunkel, John, Vaiana, Sara M, Bock, Lars V, Grubmüller, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887479/
https://www.ncbi.nlm.nih.gov/pubmed/35150281
http://dx.doi.org/10.1093/nar/gkac038