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Prediction and pan-cancer analysis of mammalian transcripts involved in target directed miRNA degradation

It is currently unknown how many RNA transcripts are able to induce degradation of microRNAs (miRNA) via the mechanism known as target-directed miRNA degradation (TDMD). We developed TDMDfinder, a computational pipeline that identifies ‘high confidence’ TDMD interactions in the Human and Mouse trans...

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Detalles Bibliográficos
Autores principales: Simeone, Ines, Rubolino, Carmela, Noviello, Teresa Maria Rosaria, Farinello, Diego, Cerulo, Luigi, Marzi, Matteo Jacopo, Nicassio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887481/
https://www.ncbi.nlm.nih.gov/pubmed/35137158
http://dx.doi.org/10.1093/nar/gkac057