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Flexible TALEs for an expanded use in gene activation, virulence and scaffold engineering

Transcription activator-like effectors (TALEs) are bacterial proteins with a programmable DNA-binding domain, which turned them into exceptional tools for biotechnology. TALEs contain a central array of consecutive 34 amino acid long repeats to bind DNA in a simple one-repeat-to-one-nucleotide manne...

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Detalles Bibliográficos
Autores principales: Becker, Sebastian, Mücke, Stefanie, Grau, Jan, Boch, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887545/
https://www.ncbi.nlm.nih.gov/pubmed/35150566
http://dx.doi.org/10.1093/nar/gkac098