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The ER membrane complex (EMC) can functionally replace the Oxa1 insertase in mitochondria

Two multisubunit protein complexes for membrane protein insertion were recently identified in the endoplasmic reticulum (ER): the guided entry of tail anchor proteins (GET) complex and ER membrane complex (EMC). The structures of both of their hydrophobic core subunits, which are required for the in...

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Detalles Bibliográficos
Autores principales: Güngör, Büsra, Flohr, Tamara, Garg, Sriram G., Herrmann, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887752/
https://www.ncbi.nlm.nih.gov/pubmed/35231030
http://dx.doi.org/10.1371/journal.pbio.3001380