Hypoxia-induced interstitial transformation of microvascular endothelial cells by mediating HIF-1α/VEGF signaling in systemic sclerosis

OBJECTIVE: The aim of this research was to systematically investigate the effects of endothelial mesenchymal transition (EndMT) induced by hypoxia on the skin microvascular remodeling of systemic sclerosis (SSc) and the underlying mechanism. METHODS: Skin tissues from SSc patients and controls were...

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Detalles Bibliográficos
Autores principales: Mao, Jing, Liu, Jiexiong, Zhou, Mei, Wang, Guiqiang, Xiong, Xia, Deng, Yongqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887755/
https://www.ncbi.nlm.nih.gov/pubmed/35231032
http://dx.doi.org/10.1371/journal.pone.0263369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887755/
https://www.ncbi.nlm.nih.gov/pubmed/35231032
http://dx.doi.org/10.1371/journal.pone.0263369

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