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Hypoxia-induced interstitial transformation of microvascular endothelial cells by mediating HIF-1α/VEGF signaling in systemic sclerosis
OBJECTIVE: The aim of this research was to systematically investigate the effects of endothelial mesenchymal transition (EndMT) induced by hypoxia on the skin microvascular remodeling of systemic sclerosis (SSc) and the underlying mechanism. METHODS: Skin tissues from SSc patients and controls were...
Autores principales: | Mao, Jing, Liu, Jiexiong, Zhou, Mei, Wang, Guiqiang, Xiong, Xia, Deng, Yongqiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887755/ https://www.ncbi.nlm.nih.gov/pubmed/35231032 http://dx.doi.org/10.1371/journal.pone.0263369 |
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