Dysfunction of parvalbumin-expressing cells in the thalamic reticular nucleus induces cortical spike-and-wave discharges and an unconscious state

Spike-and-wave discharges and an accompanying loss of consciousness are hallmarks of absence seizure, which is a childhood generalized epilepsy disorder. In absence seizure, dysfunction of the cortico-thalamo-cortico circuitry is thought to engage in abnormal cortical rhythms. Previous studies demon...

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Detalles Bibliográficos
Autores principales: Abdelaal, Manal S., Midorikawa, Mitsuharu, Suzuki, Toru, Kobayashi, Kenta, Takata, Norio, Miyata, Mariko, Mimura, Masaru, Tanaka, Kenji F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887905/
https://www.ncbi.nlm.nih.gov/pubmed/35243344
http://dx.doi.org/10.1093/braincomms/fcac010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8887905/
https://www.ncbi.nlm.nih.gov/pubmed/35243344
http://dx.doi.org/10.1093/braincomms/fcac010

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