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Ferroptosis-Specific Inhibitor Ferrostatin-1 Relieves H(2)O(2)-Induced Redox Imbalance in Primary Cardiomyocytes through the Nrf2/ARE Pathway

OBJECTIVE: Ischemic heart disease (IHD) has always been the focus of attention of many researchers in cardiovascular disease, and its pathogenesis is also very complicated. Ferroptosis may be involved in the occurrence and development of IHD. METHODS: First, primary cardiomyocytes were treated with...

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Detalles Bibliográficos
Autores principales: Sun, Chaofeng, Peng, Fang, Li, Jianfei, Cui, Xudong, Qiao, Xin, Zhu, Wangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888041/
https://www.ncbi.nlm.nih.gov/pubmed/35242242
http://dx.doi.org/10.1155/2022/4539932