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Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury

Doxorubicin (Dox) is an effective chemotherapeutic drug for the treatment of various cancers. Due to its potential fatal cardiotoxic side effects, the clinical application is often limited. Dexrazoxane (Dex) is the only drug approved by the Food and Drug Administration (FDA) for the prevention of Do...

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Detalles Bibliográficos
Autores principales: Zou, Linfeng, Liang, Bing, Gao, YuanZhen, Ye, Ting, Li, MengJiao, Zhang, Yukun, Lu, Qi, Hu, Xiaokun, Li, Huanting, Yuan, Yang, Xing, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888081/
https://www.ncbi.nlm.nih.gov/pubmed/35242876
http://dx.doi.org/10.1155/2022/6293329